Xiaoyun Wu Selected Research

DFG peptide

3/2017

Bisarylureas Based on 1H-Pyrazolo[3,4-d]pyrimidine Scaffold as Novel Pan-RAF Inhibitors with Potent Anti-Proliferative Activities: Structure-Based Design, Synthesis, Biological Evaluation and Molecular Modelling Studies.

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Xiaoyun Wu Research Topics

Disease

23	Neoplasms (Cancer) 01/2023 - 03/2010
8	Infections 01/2023 - 03/2003
7	Inflammation (Inflammations) 01/2024 - 11/2015
6	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 02/2024 - 09/2018
6	Body Weight (Weight, Body) 12/2023 - 10/2016
4	Obesity 02/2024 - 10/2016
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 10/2021
3	Hypertension (High Blood Pressure) 01/2021 - 01/2016
3	Atherosclerosis 11/2020 - 12/2019
3	Virus Diseases (Viral Diseases) 10/2017 - 07/2004
2	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 02/2024 - 12/2020
2	Insulin Resistance 02/2024 - 10/2016
2	Carcinogenesis 12/2023 - 03/2015
2	Type 2 Diabetes Mellitus (MODY) 01/2023 - 10/2016
2	Atherosclerotic Plaque (Atheroma) 08/2022 - 12/2019
2	Stomach Neoplasms (Stomach Cancer) 01/2022 - 11/2021
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2020
2	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 01/2017
2	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 11/2021
2	Glioblastoma (Glioblastoma Multiforme) 12/2021 - 02/2020
2	Weight Gain 03/2021 - 01/2018
2	Metabolic Diseases (Metabolic Disease) 01/2021 - 03/2013
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021 - 09/2017
2	Colitis 01/2020 - 11/2006
2	Hyperlipidemias (Hyperlipidemia) 11/2019 - 01/2016
2	Sarcoma (Soft Tissue Sarcoma) 03/2017 - 01/2017
2	Non-alcoholic Fatty Liver Disease 10/2016 - 11/2015
2	Hyperglycemia 10/2016 - 01/2016
2	Retinoblastoma (Glioblastoma, Retinal) 01/2012 - 05/2002
2	Acquired Immunodeficiency Syndrome (AIDS) 07/2008 - 11/2006
1	Mental Disorders (Mental Disorder) 05/2024
1	Hyperandrogenism 02/2024
1	Lung Injury 01/2024
1	Myocarditis (Carditis) 12/2023
1	Ectopic Pregnancy 12/2023
1	Ovarian Diseases (Ovarian Disease) 02/2023
1	Endometrial Neoplasms (Endometrial Cancer) 01/2023
1	Insulinoma 01/2023
1	Sialorrhea 01/2023
1	Uterine Diseases (Endometrial Disease) 01/2023
1	Pneumonia (Pneumonitis) 01/2023
1	Nervous System Diseases (Neurological Disorders) 01/2023

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 01/2023 - 05/2002
10	LipidsIBA 01/2023 - 03/2013
5	ErbB Receptors (EGF Receptor)IBA 02/2024 - 08/2016
5	CytokinesIBA 12/2023 - 11/2006
4	Type 3 Cyclic Nucleotide PhosphodiesterasesIBA 01/2023 - 02/2016
4	Phosphotransferases (Kinase)IBA 01/2022 - 03/2017
4	RNA (Ribonucleic Acid)IBA 12/2019 - 03/2010
3	CholesterolIBA 11/2020 - 11/2015
3	6- (4- (diethylamino)- 3- nitrophenyl)- 5- methyl- 4,5- dihydropyridazin- 3(2H)- oneIBA 01/2020 - 02/2016
2	ZincIBA 02/2024 - 01/2021
2	Glucose (Dextrose)FDA LinkGeneric 01/2024 - 01/2023
2	Messenger RNA (mRNA)IBA 02/2023 - 03/2010
2	Matrix Metalloproteinases (MMPs)IBA 01/2023 - 02/2020
2	Biomarkers (Surrogate Marker)IBA 12/2022 - 11/2021
2	BromidesIBA 11/2022 - 01/2022
2	IridiumIBA 01/2022 - 01/2022
2	Therapeutic UsesIBA 01/2022 - 01/2020
2	osimertinibIBA 01/2022 - 02/2020
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 11/2006
2	Peroxidase (Myeloperoxidase)IBA 01/2022 - 01/2017
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 11/2020
2	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2021 - 11/2019
2	CrizotinibIBA 10/2019 - 09/2018
2	oxidized low density lipoproteinIBA 01/2018 - 11/2015
2	AntibodiesIBA 01/2018 - 11/2006
2	Triglycerides (Triacylglycerol)IBA 01/2018 - 11/2015
2	pyrimidineIBA 03/2017 - 08/2016
1	Dopamine (Intropin)FDA LinkGeneric 05/2024
1	CalciumIBA 02/2024
1	MineralsIBA 02/2024
1	MagnesiumIBA 02/2024
1	SeleniumIBA 02/2024
1	IronIBA 02/2024
1	OzoneIBA 01/2024
1	pro-brain natriuretic peptide (1-76)IBA 12/2023
1	Troponin IIBA 12/2023
1	MB Form Creatine KinaseIBA 12/2023
1	Brain Natriuretic Peptide (Natrecor)FDA Link 12/2023
1	Hormones (Hormone)IBA 12/2023
1	Methotrexate (Mexate)FDA LinkGeneric 12/2023
1	Transcription Factors (Transcription Factor)IBA 02/2023
1	Type A Botulinum Toxins (Botox)FDA Link 01/2023
1	Botulinum Toxins (Botulinum Toxin)IBA 01/2023
1	Palmitic Acid (Hexadecanoic Acid)IBA 01/2023
1	Leu Transfer RNAIBA 01/2023
1	Silybin (Lagosa)IBA 01/2023
1	Viral RNAIBA 01/2023
1	Plant RNAIBA 01/2023
1	DNA-Directed RNA Polymerases (RNA Polymerase)IBA 01/2023
1	MetalsIBA 01/2023
1	Adenosine Triphosphate (ATP)IBA 01/2023
1	4,4'-hexafluorisopropylidene diphenolIBA 01/2023
1	bisphenol BIBA 01/2023

Therapy/Procedure

11	Therapeutics 01/2023 - 05/2015
2	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2022 - 11/2021
1	Tracheotomy 01/2023
1	Cannula 01/2023
1	Immunotherapy 01/2023